Marx made his debut as a major character in the Kirby Super Star game Milky Way Wishes. In the game, Marx asks Kirby to gather the power of surrounding stars to awaken the giant comet, Galactic Nova, so the sun and moon can stop fighting. Once Kirby finds and awakes Nova, Marx appears and asks it for the ability to rule Pop Star. Nova grants Marx's wish, causing him to become larger and grow crystal wings. After Kirby defeats him, Marx is sent flying into Nova, their impact causing them to explode.
Marx appears as the final boss of Milky Way Wishes, and, subsequently, the whole entirety of Kirby Super Star. He also appears as the final boss of The Arena sub-game. In The True Arena sub-game from Kirby Super Star Ultra, Marx's unconscious body absorbs the remaining energy from Nova, transforming him into Marx Soul.
Marx's boss theme from Brawl returns as a music track.
As a boss
In Ultimate, Marx appears as a boss at the end of Kirby's, Rosalina & Luma's, and Inkling's Classic Mode run, as well as in Adventure Mode: World of Light. Sephiroth also faces Marx during his Classic Mode, as with other regular bosses in the game, though not as the final round. Normally, Vs. Marx plays during the battle, but Calamari Inkantation plays in Inkling's route, and Galeem / Dharkon plays during the boss rush. His voice appears similar to the one heard in Kirby Star Allies. His battle takes place in the Mysterious Dimension, which is in The Dark Realm.
Marx's boss fight starts off with him using the moves that he similarly used against Kirby in Kirby Super Star. When the fighter gets close, he will teleport some distance away from them. Marx has three moves that he didn't have in Kirby Super Star or Kirby Super Star Ultra: an attack where his eyes turn black and black balls spawn from them, an attack where he creates vein-like growths, and an attack where his eyes enlarge and fire lasers.
Upon defeat, Marx screams and starts flying around the stage sporadically. His wings break off as he reverts to his smaller form and lands face first on the ground. His body also temporarily alights in a purple flame that simmers out just before the screen fades out.
As a costume
Marx's hat is available for the Mii Fighters in the shop.
Marx also appears in the game as a spirit in both his normal and true form.