Megavitamins is Dr. Mario's neutral special move. Megavitamins are similar to Mario's Fireballs in that they are a medium-short-ranged projectile that bounces along the ground. However, they bounce higher, fall faster, do more damage (8%), and have distinctive sound effects from the original Dr. Mario upon firing, bouncing, and hitting; despite being a physical pill as opposed to a ball of flame, they can still be absorbed. They are also used in Dr. Mario's taunt, in which he tosses a non damaging Megavitamin up and catches it. The colour of each Megavitamin produced (each half can be red, yellow, or blue) is random and has no gameplay effect.
A Megavitamin appears as a sticker in Brawl.
Megavitamins come in six color combinations of red, blue and yellow. Dr. Mario uses these capsules by tossing them into contaminated bottles to destroy viruses. The origin of these wonder pills is a mystery, but the most likely theory is that they're the result of Dr. Mario's lifelong efforts to find a cure for the common cold.
In Dr. Mario, these were used to eliminate viruses. When the player lines up four vitamins and/or viruses of the same colour, the vitamins and the viruses are destroyed.