Dr. Mario (game)

Dr. Mario (, Doctor Mario) is a 1990 puzzle video game for the Nintendo Entertainment System and the Game Boy. In the game, Mario, in his Dr. Mario persona, uses vitamins to destroy three different types of viruses by lining up three vitamins the same color as the virus, bearing some similarities with Tetris. The Game Boy version of the game appears in as a Masterpiece, and must be unlocked by clearing 10-Man Smash with Dr. Mario without taking damage.

Fighter
Dr. Mario made his debut in this game. The viruses also appear as trophies and stickers.

Moves
The Megavitamins that are used for Dr. Mario's neutral special move and his Final Smash originate from this game.

Music
The "Fever", "Chill", and "Chill Ver. 2" tracks originated from this game.